Eric Dane, best known for his roles on Grey’s Anatomy and Euphoria, has died at the age of 53. Dane’s passing comes nearly one year after he publicly revealed that he had been diagnosed with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, in 2025.
“With heavy hearts, we share that Eric Dane passed on Thursday afternoon following a courageous battle with ALS,” his family said in a statement to People.
“He spent his final days surrounded by dear friends, his devoted wife, and his two beautiful daughters, Billie and Georgia, who were the center of his world. Throughout his journey with ALS, Eric became a passionate advocate for awareness and research, determined to make a difference for others facing the same fight.”
© VarietyThe statement continues, “He will be deeply missed, and lovingly remembered always. Eric adored his fans and is forever grateful for the outpouring of love and support he’s received. The family has asked for privacy as they navigate this impossible time.” He is survived by his daughters, Billie and Georgia.
Dane first became widely known for his portrayal of Dr. Mark Sloan, also known as “McSteamy,” on ‘Grey’s Anatomy.’ Introduced in the show’s second season in 2006, his character became a series regular due to strong fan response and remained until season 8. He later reprised the role in subsequent seasons.
© SAUL LOEBIn 2019, he began playing Cal Jacobs on HBO’s ‘Euphoria,’ appearing in 12 episodes across the first two seasons and returning for the third season.
After announcing his diagnosis, Dane spoke openly about his decision to share his health journey. “I have been diagnosed with ALS,” he told the publication in 2025. “I am grateful to have my loving family by my side as we navigate this next chapter.” He added at the time that he would continue filming season 3 of ‘Euphoria.’
© NBCIn an interview with The Washington Post, he reflected on his advocacy work following his diagnosis. “I have been an open book about certain things in my life. This is something I felt compelled to share with people,” he said. “I don’t really have a dog in the fight, per se, when it comes to worrying about what people are going think about me. This is more of a: ‘How can I help? How can I be of some service?’” “Not to be overly morbid,” he added, “but you know, if I’m going out, I’m gonna go out helping somebody.”
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